Gene interactions and pathways from curated databases and text-mining

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CDKN1B — MAPK3

Text-mined interactions from Literome

Kress et al., Cell communication and signaling : CCS 2010 : However, the reduction of Erk1/2 activity with MEK inhibitors generally abolished cell growth but only led to an increase of cellular p27Kip1 levels in CRC cells with high Erk1/2 activity levels
Kawada et al., Oncogene 1997 : Inhibition of the activation of mitogen activated protein ( MAP ) kinase by cyclic AMP elevating agents and a MEK inhibitor prevented the oncogenic Ras induced degradation of p27Kip1