Gene interactions and pathways from curated databases and text-mining

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CDK9 — POLR2E

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Ping et al., J Biol Chem 2001 : DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation
Shore et al., Gene 2003 : Positive transcription factor b (P-TEFb) is required for RNA polymerase II to make the transition from abortive to productive elongation
Jang et al., Mol Cell 2005 : The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription
Bark-Jones et al., Oncogene 2006 : EBV EBNA 2 stimulates CDK9 dependent transcription and RNA polymerase II phosphorylation on serine 5
Schönichen et al., Biochemistry 2010 : Transcription elongation is regulated by the cellular protein Hexim1, which inhibits phosphorylation of RNA polymerase II by interacting with the positive transcription elongation factor P-TEFb
Flynn et al., Proc Natl Acad Sci U S A 2011 : Antisense RNA polymerase II divergent transcripts are P-TEFb dependent and substrates for the RNA exosome
Bowman et al., Development 2013 : Phosphorylation of RNA polymerase II is independent of P-TEFb in the C. elegans germline