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CDK8 — HIF1A

Text-mined interactions from Literome

Lou et al., PloS one 2010 : The inhibitory effects of camptothecin on HIF-1alpha expression but not that of mitomycin C and NSC-652287 were dependent on cyclin dependent kinase activity
Galbraith et al., Cell 2013 (Neoplasms) : The Mediator associated kinase CDK8 , but not the paralog CDK19, is required for induction of many HIF1A target genes ... HIF1A induces binding of CDK8-Mediator and the super elongation complex ( SEC ), containing AFF4 and CDK9, to alleviate RNAPII pausing