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CDH5 — IGF1
Text-mined interactions from Literome
Pennisi et al., Cancer Res 2002
(Breast Neoplasms...) :
Our findings strongly suggest that the
IGF-IR plays a role in the stabilization of the
E-cadherin-catenin complex, thereby providing one possible explanation for the association between low levels of IGF-IR and a higher risk of mammary tumor metastasis
Devi et al., Biochim Biophys Acta 2011
(Diabetic Retinopathy) :
Furthermore,
IGF-1 reduces the level of intercellular adherence molecule
VE-cadherin and increases monolayer permeability in TR-iBRB2 cells when measured by FITC-dextran leakage ... The
effect of
IGF-1 on
VE-cadherin and membrane permeability is absent in TR-iBRB2 cells expressing the GSK-3ß ( S9A )