Gene interactions and pathways from curated databases and text-mining

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CDH5 — IGF1

Text-mined interactions from Literome

Pennisi et al., Cancer Res 2002 (Breast Neoplasms...) : Our findings strongly suggest that the IGF-IR plays a role in the stabilization of the E-cadherin-catenin complex, thereby providing one possible explanation for the association between low levels of IGF-IR and a higher risk of mammary tumor metastasis
Devi et al., Biochim Biophys Acta 2011 (Diabetic Retinopathy) : Furthermore, IGF-1 reduces the level of intercellular adherence molecule VE-cadherin and increases monolayer permeability in TR-iBRB2 cells when measured by FITC-dextran leakage ... The effect of IGF-1 on VE-cadherin and membrane permeability is absent in TR-iBRB2 cells expressing the GSK-3ß ( S9A )