Gene interactions and pathways from curated databases and text-mining

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CASP7 — CDC42

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Bellosillo et al., Blood 2001 (Lymphoproliferative Disorders) : In addition, no cells with a hypodiploid DNA content were detected and R-CDC was not prevented by a broad-spectrum caspase inhibitor, suggesting a caspase independent mechanism
Ito et al., J Clin Invest 2010 (Bone Resorption) : We further demonstrated that Cdc42 modulated M-CSF stimulated cyclin D expression and phosphorylation of Rb and induced caspase 3 and Bim, thus contributing to osteoclast proliferation and apoptosis rates