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AKT1 — CDC25B
Text-mined interactions from Literome
Feng et al., Biol Reprod 2007
:
Therefore, AKT causes the activation of MPF and strongly promotes the development of one-cell stage mouse fertilized eggs by inducing
AKT dependent phosphorylation of
CDC25B , a member of the CDC25 phosphatase family
Chen et al., Cancer Res 2009
(Breast Neoplasms...) :
Additionally, expression of
CDC25B ( S375A )
inhibited the
AKT activation by rapamycin, indicating that phosphorylation of CDC25B is critical for CDC25B activity and its ability to transduce rapamycin induced oncogenic AKT activity