Gene interactions and pathways from curated databases and text-mining

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CD8B — IL22

Text-mined interactions from Literome

Chaput et al., Gut 2009 (Adenocarcinoma...) : Finally, interleukin 6 and TGF beta 1 synergistically induced the generation of CD8 ( + ) CD25 ( + ) Foxp3 ( + ) T cells ex vivo
Contreras et al., J Immunol 2010 : Compared to CD26 ( - ) DCs, the sheep CD26 ( + ) DCs show 1 ) potent stimulation of allogeneic naive CD8 ( + ) T cells with high selective induction of the Ifngamma and Il22 genes ; 2 ) dominant efficacy in activating specific CD8 ( + ) T cells against exogenous soluble Ag ; and 3 ) selective expression of functional pathways associated with high capacity for Ag cross-presentation
Ma et al., Scand J Immunol 2011 (Colonic Neoplasms) : This study aims to investigate the role of tumour derived Foxhead box P3 (Foxp3) ( + ) interleukin (IL)-17 ( + ) T cells on suppressing tumour-specific CD8 ( + ) T cells
Höllsberg et al., Proc Natl Acad Sci U S A 1995 : CD8 T-cell stimulation with the wild-type peptide antigen led to activation of p56lck kinase activity, interleukin 2 secretion, cytotoxicity, and clonal expansion