Gene interactions and pathways from curated databases and text-mining

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CD86 — MAPK3

Text-mined interactions from Literome

Miyazawa et al., J Toxicol Sci 2008 (MAP Kinase Signaling System) : In particular, inhibition of p38 MAPK suppressed CD86 , CD54, and CD40 expression induced by DNCB and CD86 expression induced by NiSO ( 4 ) while inhibition of ERK pathways suppressed CD86, CD54 and CD40 expression induced by DNCB and NiSO ( 4 )
Yang et al., Biol Pharm Bull 2008 : Inhibition of NF-kappaB and extracellular signal regulated kinases ( ERK1/2 ) activity by specific inhibitors blunted the effect of semi-vioxanthin on the up-regulation of CD80, CD86 and MHCII expression, but neither p38 MAPK nor c-Jun N-terminal kinase (JNK) inhibitor had this effect