Gene interactions and pathways from curated databases and text-mining

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CD69 — MAPK3

Text-mined interactions from Literome

Chau et al., Transplantation 2001 : Short exposure of human peripheral blood T lymphocytes to HuM291 caused a partial agonist type of signaling through the TCR characterized by incomplete phosphorylation of TCR zeta, failure to activate ZAP-70 and to phosphorylate LAT but activation of ERK-1/-2 and subsequent up-regulation of CD69 expression
Kim et al., Biochem Biophys Res Commun 2009 : Hph-1-ZAP-70-Y319F inhibited the phosphorylation of ZAP-70-Tyr319, LAT-Tyr191, and p44/42 MAPK induced by TcR stimulation, NFAT- and AP-1 mediated gene transcription, and the induction of CD69 expression and IL-2 secretion
Wöbke et al., PloS one 2013 : Comparative studies with different inhibitors for mitogen activated protein kinases ( MAPKs ) revealed that MAPK signalling is involved in CD69 gene regulation, whereas 5-lipoxygenase gene expression was only partly affected
Denny et al., J Biol Chem 1999 : Activation of extracellular signal regulated kinase ( ERK ) and MAPK kinase ( MEK ), as well as the induction of CD69 expression, was greatly impaired in JCaM1/LckW97A cells