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CASP5 — CCNH

Text-mined interactions from Literome

Koeppel et al., J Biol Chem 2004 : Activation of full-length PAK-2 by Rac or Cdc42 stimulates cell survival and protects cells from cell death, whereas caspase activated PAK-2p34 induces a cell death response ... Although many proteins have been shown to interact with and regulate full-length PAK-2, little is known about the regulation of caspase activated PAK-2p34 ... Here, we identify PS-GAP as a regulator of caspase activated PAK-2p34
Marlin et al., Mamm Genome 2011 : Functional PAK-2 knockout and replacement with a caspase cleavage-deficient mutant in mice reveals differential requirements of full-length PAK-2 and caspase activated PAK-2p34 ... In this study we use functional knockout of PAK-2 and gene replacement with the caspase cleavage-deficient PAK-2D212N mutant to differentiate the biological functions of full-length PAK-2 and caspase activated PAK-2p34