Gene interactions and pathways from curated databases and text-mining

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CCND3 — STAT3

Pathways - manually collected, often from reviews:

  • KEGG Jak-STAT signaling pathway: STAT1/STAT2/STAT3/STAT4/STAT5A/STAT5B/STAT6 → CCND1/CCND2/CCND3 (gene expression, expression)

Text-mined interactions from Literome

Odajima et al., J Biol Chem 2000 (Cell Transformation, Neoplastic) : During N17- and STAT3D induced growth suppression, expression of cyclin D2, cyclin D3 , c-myc, and c-fos was suppressed by N17, whereas that of cyclin D2, cyclin E, and c-myc was suppressed by STAT3D
Turgeon et al., J Cell Biochem 2013 (Inflammation) : Suz12 depleted cells achieved higher cell densities after confluence, with increased cyclin D2 and cyclin D3 protein levels, and increased STAT3 activation in post-confluent cells