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CCND1 — IGF2

Text-mined interactions from Literome

Cui et al., Mol Endocrinol 2003 (Breast Neoplasms) : Second, whereas PR and cyclin D1 are both ER up-regulated, IGF-I increased cyclin D1 levels while decreasing PR levels
Hartmann et al., Am J Pathol 2005 (Cerebellar Neoplasms...) : In GCPs, a synergistic effect of Shh and Igf-II on proliferation and gli1 and cyclin D1 mRNA expression was found
Jiang et al., J Cell Biochem 2006 (Hypertrophy) : Surprisingly, IGF-1 activates the expression of both cyclin D1 and cell-cycle arrest factor, p21Cip1 parallely
Fukushima et al., Endocrinology 2008 : In contrast, IGF-I dependent PI 3-kinase activation was required for the increase in cyclin D1 mRNA levels and degradation of p27 ( Kip1 )
Jones et al., Mol Cancer Res 2008 (Mammary Neoplasms, Animal) : Characterization of a novel primary mammary tumor cell line reveals that cyclin D1 is regulated by the type I insulin-like growth factor receptor
Borowiec et al., Biochim Biophys Acta 2011 (Ion Channel Gating) : As expected, IGF-1 increased cyclin D1 and E expression of MCF-7 cells in a cyclic manner, whereas the increase of CDK4 and 2 levels was sustained
Yan et al., Dev Neurobiol 2013 : Furthermore, 5'-end deletions and mutation analysis of this promoter revealed that a cAMP response element ( CRE ) within -174 base pair ( bp ) upstream of the transcription start site is crucial to the IGF induced increase in cyclin D1 transcription