Gene interactions and pathways from curated databases and text-mining

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CCK — NPY

Text-mined interactions from Literome

Arnelo et al., Brain Res 2000 (Anorexia) : In the 5-day, 25 pmol/kg-min group, neuropeptide Y (NPY) increased in the hypothalamus ( P < 0.01 ) and CCK increased in the hypothalmus and striatum ( both P < 0.05 )
Bi et al., Neuropeptides 2002 (Body Weight) : These data suggest an important role for CCK in controlling NPY expression in a population of non-leptin regulated hypothalamic neurons
Tirassa et al., Neuropharmacology 2005 : CCK-8 prevents the development of kindling and regulates the GABA and NPY expression in the hippocampus of pentylenetetrazole ( PTZ ) -treated adult rats
Volkoff et al., Gen Comp Endocrinol 2005 : In goldfish, nutritional status can modify the expression of mRNAs encoding a number of these peptides, which provides further evidence for their roles as appetite regulators : ( 1 ) brain mRNA expression of CCK , CART, tachykinins, galanin, ghrelin, and NPY undergo peri-prandial variations ; and ( 2 ) fasting increases the brain mRNA expression of NPY , AgRP, and ghrelin as well as serum ghrelin levels, and decreases the brain mRNA expression of tachykinins, CART, and CCK
Bi et al., Peptides 2007 : A role for CCK in controlling DMH NPY expression is demonstrated by the down-regulation of DMH NPY by parenchymal DMH CCK administration in intact rats
Relling et al., J Anim Sci 2010 (Body Weight) : We conclude that insulin, ghrelin, CCK , and GLP-1 may regulate DMI in sheep by regulating the hypothalamic gene expression of NPY , AgRP, and POMC
Bi et al., Neuropeptides 2012 : Npy gene expression in the DMH is regulated by brain cholecystokinin (CCK) and other yet to be identified molecules