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CCK — NPY
Text-mined interactions from Literome
Arnelo et al., Brain Res 2000
(Anorexia) :
In the 5-day, 25 pmol/kg-min group,
neuropeptide Y (NPY) increased in the hypothalamus ( P < 0.01 ) and
CCK increased in the hypothalmus and striatum ( both P < 0.05 )
Bi et al., Neuropeptides 2002
(Body Weight) :
These data suggest an important
role for
CCK in controlling
NPY expression in a population of non-leptin regulated hypothalamic neurons
Tirassa et al., Neuropharmacology 2005
:
CCK-8 prevents the development of kindling and
regulates the GABA and
NPY expression in the hippocampus of pentylenetetrazole ( PTZ ) -treated adult rats
Volkoff et al., Gen Comp Endocrinol 2005
:
In goldfish, nutritional status can modify the expression of mRNAs encoding a number of these peptides, which provides further evidence for their roles as appetite regulators : ( 1 ) brain mRNA expression of
CCK , CART, tachykinins, galanin, ghrelin, and NPY undergo peri-prandial variations ; and ( 2 ) fasting
increases the brain mRNA expression of
NPY , AgRP, and ghrelin as well as serum ghrelin levels, and decreases the brain mRNA expression of tachykinins, CART, and CCK
Bi et al., Peptides 2007
:
A
role for
CCK in controlling DMH
NPY expression is demonstrated by the down-regulation of DMH NPY by parenchymal DMH CCK administration in intact rats
Relling et al., J Anim Sci 2010
(Body Weight) :
We conclude that insulin, ghrelin,
CCK , and GLP-1 may
regulate DMI in sheep by regulating the hypothalamic gene expression of
NPY , AgRP, and POMC
Bi et al., Neuropeptides 2012
:
Npy gene expression in the DMH is
regulated by brain
cholecystokinin (CCK) and other yet to be identified molecules