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CCK — MAPK3

Text-mined interactions from Literome

Dabrowski et al., Pancreas 2000 : Whereas CCK induced activation of MAPK or JNK was totally or partially blocked by protein kinase C ( PKC ) inhibitor GF-109203X, ROS induced activation of MAPK, JNK, and p38 MAPK was PKC independent
Siegel et al., J Biol Chem 2001 (Calcium Signaling...) : Rapid phosphorylation of p38 ( MAPK ) and p42/44(MAPK) could also be observed in the presence of cholecystokinin (CCK) , which also causes activation of cPLA2
Meng et al., World J Gastroenterol 2002 (Endotoxemia...) : The p38 MAPK expression increased significantly in LPS group ( 5.84 times of control ) and CCK-8 increased the activation of p38 MAPK in ES rats ( 10.74 times of control ) ... CCK-8 reverses the decrease of MAP in ES rats and has inhibitory effect on the gene and protein expression of TNF-alpha in spleen, and p38 MAPK may be involved in its signal transduction mechanisms
Meng et al., Sheng Li Xue Bao 2002 (Shock, Septic) : These results suggest that CCK-8 can alleviate the LPS induced decrease in MAP of ES rats and exert an inhibitory effect on the overproduction of proinflammatory cytokines, and that p38 MAPK may be involved in its signal transduction mechanisms
Clemons et al., Pancreas 2002 (Acute Disease...) : Both cerulein and cholecystokinin activate mitogen activated protein ( MAP) kinase (ERK1/2 ) in vivo and in isolated pancreatic acini
Williams et al., Pharmacol Toxicol 2002 : CCK activation of p38 MAPK also plays a role in regulating the actin cytoskeleton through phosphorylation of the small heat shock protein HSP27
Huang et al., Regul Pept 2007 (Colonic Neoplasms) : The effects of CCK-2i4svR activation on phosphorylation of ERK1/2, p38 ( MAPK ) and JNK were examined by using immunoblotting
Campos et al., Endocrinology 2012 (MAP Kinase Signaling System) : CCK induced reduction of food intake and hindbrain MAPK signaling are mediated by NMDA receptor activation
Duan et al., Am J Physiol 1994 : Cholecystokinin rapidly activates mitogen activated protein kinase in rat pancreatic acini
Taniguchi et al., Oncogene 1994 : Among them, mitogen activated protein ( MAP ) kinase was tyrosine phosphorylated and activated in response to CCK-8 , as was induced by platelet derived growth factor ( PDGF )
Groblewski et al., Gastroenterology 1997 : Cholecystokinin stimulated mitogen activated protein kinase activated protein ( MAPKAP) kinase 2 activity was measured after immunoprecipitation of the kinase
Dabrowski et al., Digestion 1997 (Carcinoma, Acinar Cell...) : It was recently found that cholecystokinin (CCK) activates mitogen activated protein kinases ( MAPK ) in isolated rat pancreatic acini ... CCK significantly increased p44 MAPK and p42 MAPK activities in AR42J cells ... In conclusion, both CCK-A and CCK-B receptors activate MAPK in AR42J cells and in transfected CHO cells
Dabrowski et al., Am J Physiol 1997 : The EGF induced increase of MAPK activity was transient, with only a slight elevation after 30 min, whereas CCK stimulated MAPK remained at a high level of activation to 60 min ... The protein kinase C inhibitor GF-109203X abolished the activation by phorbol ester and inhibited the effect of CCK by 78 % but had no effect on EGF activated MAPK activity
Némoz-Gaillard et al., Biochem J 1998 : Additionally, PKC activation appeared to be required for both MAPK dependent ( early ) and -independent ( late ) CCK responses to bombesin ... It is concluded that the early CCK secretory response of STC-1 cells to bombesin involves MAPK pathway activation through a PKC dependent mechanism, whereas the late phase of bombesin induced CCK secretion, that also requires PKC, appears to result from a MAPK independent process
Tateishi et al., Pancreas 1998 (Carcinoma, Ductal, Breast...) : CCK-8 at 10 ( -7 ) M induced 1.5-fold increases in the phosphorylation of MAPK and of c-Jun by JNKs, respectively