Gene interactions and pathways from curated databases and text-mining

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CCDC88A — STAT3

Text-mined interactions from Literome

Dunkel et al., J Biol Chem 2012 (Breast Neoplasms...) : STAT3 protein up-regulates Ga-interacting vesicle associated protein ( GIV ) /Girdin expression, and GIV enhances STAT3 activation in a positive feedback loop during wound healing and tumor invasion/metastasis
Cardoso et al., PloS one 2012 (Adenocarcinoma...) : Overall, this work demonstrates that the transcriptional activity of STAT3 is directly regulated by the redox function of APE1/Ref-1 , and that concurrent blockade of STAT3 and APE1/Ref-1 redox synergize effectively inhibit critical PDAC cell functions