Gene interactions and pathways from curated databases and text-mining

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CBL — EPO

Text-mined interactions from Literome

Hanazono et al., Acta Haematol 1996 : Furthermore, we have shown that the proto-oncogene c-cbl product (c-Cbl) is also tyrosine phosphorylated by stimulation with GM-CSF or Epo and is constitutively associated with the SH3 domain of Grb2/Ash in UT-7
Barber et al., Blood 1997 : Erythropoietin and interleukin-3 activate tyrosine phosphorylation of CBL and association with CRK adaptor proteins
Chin et al., Biochem Biophys Res Commun 1997 : Erythropoietin and IL-3 induce tyrosine phosphorylation of CrkL and its association with Shc, SHP-2, and Cbl in hematopoietic cells ... The present study demonstrates that erythropoietin (Epo) and IL-3 induce tyrosine phosphorylation of the SH2/SH3 containing adapter protein CrkL and its transient association with tyrosine phosphorylated SHP-2, Shc, and Cbl in a murine IL-3 dependent cell line, 32D, expressing the Epo receptor (EpoR)