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CASP8 — CHUK
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
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IRef Biogrid Interaction:
CHUK
—
CASP8
(physical association, affinity chromatography technology)
Chaudhary et al., Oncogene 2000
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MIPS CORUM CASP8-CHUK-IKBKB-MALT1-BCL10 complex:
CASP8-CHUK-IKBKB-MALT1-BCL10 complex complex (BCL10-CASP8-CHUK-IKBKB-MALT1)
Su et al., Science 2005
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MIPS CORUM BCL10-CHUK-BCL10-IKBKB complex:
BCL10-CHUK-BCL10-IKBKB complex complex (BCL10-CASP8-CHUK-IKBKB)
Su et al., Science 2005
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IRef Corum Interaction:
Complex of IKBKB-CHUK-BCL10-CASP8-MALT1
(association, coimmunoprecipitation)
Su et al., Science 2005
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IRef Corum Interaction:
Complex of CASP8-BCL10-CHUK-IKBKB
(association, coimmunoprecipitation)
Su et al., Science 2005
-
IRef Hprd Interaction:
CHUK
—
CASP8
(in vivo)
Chaudhary et al., Oncogene 2000
-
IRef Innatedb Interaction:
CHUK
—
CASP8
(unknown, -)
Chaudhary et al., Oncogene 2000
-
IRef Ophid Interaction:
CHUK
—
CASP8
(aggregation, confirmational text mining)
Chaudhary et al., Oncogene 2000
-
IRef Ophid Interaction:
CHUK
—
CASP8
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Chen et al., Crit Care Med 2007
(Burns...) :
IKK blocks
caspase 3 expression by up-regulating BCL-xL and cellular FLICE inhibitory protein expression
Oh et al., J Pharmacol Exp Ther 2011
(Inflammation...) :
In activated human mast cells, the receptor interacting protein 2 (RIP2), I?B kinase ( IKK ) -ß, nuclear factor-?B ( NF-?B ) /RelA, and
caspase-1 activation were increased, but increased RIP2,
IKK-ß , NF-?B/RelA, and caspase-1 activation were
inhibited by the treatment of IPT