Gene interactions and pathways from curated databases and text-mining

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ARF6 — CASP1

Text-mined interactions from Literome

Nakazawa et al., J Biol Chem 2003 : We also found that ARF evokes cytochrome c release from mitochondria, decreases mitochondrial membrane potential, and activates pro-caspase-9 to induce apoptosis
Liu et al., Acta Pharmacol Sin 2005 (Acute Kidney Injury) : To study the effect of selective interleukin-1beta converting enzyme ( ICE, caspase-1 ) inhibitor on ischemic acute renal failure ( ARF )
Homsi et al., Kidney Int 2006 (Acute Kidney Injury...) : Caspase-1 inhibitor attenuated Gly-ARF but not tubular injury suggesting glomerular hemodynamic improvement