◀ Back to IGF1
CANX — IGF1
Text-mined interactions from Literome
Grzelkowska-Kowalczyk et al., Cell Mol Biol Lett 2010
:
Pretreatment of myogenic cells with IL-1beta did not modify the
IGF-I stimulated phosphorylation of PKB, p70 ( S6k ), p42(MAPK) and
p90 ( rsk )
Thimmaiah et al., Cancer Res 2010
(Rhabdomyosarcoma) :
Results indicate that
IGF-I signaling to Bad
requires activation of PI3K and PKC ( mu, theta, epsilon ) but not mTOR, Ras-extracellular signal regulated kinase 1/2, protein kinase A, or
p90 ( RSK )
Zoubeidi et al., Cancer Res 2010
(MAP Kinase Signaling System...) :
Hsp27 overexpression increases
IGF-I induced phosphorylation of Erk,
p90Rsk , and Akt ... Conversely, Hsp27 knockdown abrogates
IGF-I induced phosphorylation of Erk,
p90Rsk , and Akt, thereby destabilizing Bad/14-3-3 complexes and increasing apoptotic rates