Matsushita et al., J Biol Chem 1999
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In intact PC12 cells, activation of PKA with forskolin resulted in a rapid inhibition of both CaMKK and CaMKI activity ... These results indicate that in vitro and in intact cells the CaMKK/CaMKI cascade is subject to inhibition by PKA mediated phosphorylation of CaMKK Davare et al., J Biol Chem 2004
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Here we report an additional PKA dependent regulation of CaMKK through its interaction with protein 14-3-3