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CAMK4 — MAPK3

Pathways - manually collected, often from reviews:

• KEGG Cholinergic synapse: CAMK2A/CAMK2B/CAMK2D/CAMK2G/CAMK4 → MAPK1/MAPK3 (protein-protein, activation)

Text-mined interactions from Literome

Rosengart et al., Shock 2000 : Inhibition of CaMK IV , both after adherence and in non-adherent monocytes, significantly inhibited LPS induced ERK 1/2 activation and abrogated TNFalpha production by up to 75 % ... These data suggest that the function of CaMK II in TNFalpha production by adherent monocytes occurs during adhesion, is mediated in part by activation of ERK 1/2 , and appears to `` prime '' the monocyte for enhanced cytokine production
Cuschieri et al., Shock 2003 (MAP Kinase Signaling System...) : CaMK blockade inhibited LPS induced ERK 1/2 and JNK but enhanced p38 activity ... Altered CaMK activity resulted in dysregulated mitogen activated protein kinase signaling, demonstrated by reduced ERK 1/2 and JNK activity but enhanced p38 activity
Ahi et al., Behav Brain Res 2004 : Inhibition of CaMK II did not affect fear conditioning and reduced the phosphorylation of Erk-1/2 , Elk-1, CREB, and p90Rsk-1 only transiently, whereas Mek-1/2 inhibition was ineffective in all experiments