Gene interactions and pathways from curated databases and text-mining

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C1ORF228 — IL12A

Text-mined interactions from Literome

Matsunaga et al., Am J Respir Cell Mol Biol 2001 (Legionnaires' Disease) : Analysis of IL-12 p40 responses of both macrophage types to Lp-V infection assessed by reverse transcriptase/polymerase chain reaction revealed induction of increased message levels, but significant levels were induced only slowly
Xu et al., J Immunol 2001 (Malaria) : We analyzed the mechanism that causes suppression of IL-12 p40 gene induction during Plasmodium berghei infection ... Therefore, the inhibition of the IL-12 p40 gene induction appeared to be regulated at transcriptional regulation level of the gene
Khan et al., Blood 2006 : Endogenous accumulation of H2O2/ROSs in macrophages treated with alloxan resulted in IL-12 p40 inhibition
Olleros et al., Immunology 2007 (Granuloma...) : Interleukin (IL)-12p40 , a subunit of IL-12p70 and IL-23, has previously been shown to inhibit IL-12p70 activity and interferon-gamma (IFN-gamma) production
Takeshima et al., Infect Immun 2009 (Gastritis...) : Therefore, we investigated IL-12 p40 mRNA induction by H. pylori in gastric epithelial cells and T cells
Chong et al., Infect Immun 1996 : By 4 h postexposure, viable organisms had induced a 27-fold increase in IL-12 p40 mRNA levels while killed organisms had induced a 9-fold increase in IL-12 p40 mRNA levels
Aloisi et al., J Immunol 1997 : Combined stimulation with IFN-gamma/LPS enhances IL-12 p40 secretion and induces IL-12 p75 secretion by microglia
Kishikawa et al., Toxicol Appl Pharmacol 1997 (Listeriosis) : Support for the former hypothesis is based on the observation that Pb induced elevated levels of p40 splenic messenger RNA since increased p40 expression would result from lack of IL-12 formation
Yoshimoto et al., J Immunol 1998 (Disease Susceptibility...) : To investigate the antagonistic effect of IL-12 p40 on IL-12 activity in vivo, we generated transgenic ( Tg ) mice in which p40 gene was regulated by a liver-specific promoter