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C1ORF228 — IL12A
Text-mined interactions from Literome
Matsunaga et al., Am J Respir Cell Mol Biol 2001
(Legionnaires' Disease) :
Analysis of
IL-12 p40 responses of both macrophage types to Lp-V infection assessed by reverse transcriptase/polymerase chain reaction revealed induction of increased message levels, but significant levels were induced only slowly
Xu et al., J Immunol 2001
(Malaria) :
We analyzed the mechanism that causes suppression of
IL-12 p40 gene
induction during Plasmodium berghei infection ... Therefore, the inhibition of the
IL-12 p40 gene
induction appeared to be regulated at transcriptional regulation level of the gene
Khan et al., Blood 2006
:
Endogenous accumulation of H2O2/ROSs in macrophages treated with alloxan resulted in
IL-12 p40 inhibition
Olleros et al., Immunology 2007
(Granuloma...) :
Interleukin
(IL)-12p40 , a subunit of IL-12p70 and IL-23, has previously been shown to
inhibit IL-12p70 activity and interferon-gamma (IFN-gamma) production
Takeshima et al., Infect Immun 2009
(Gastritis...) :
Therefore, we investigated
IL-12 p40 mRNA
induction by H. pylori in gastric epithelial cells and T cells
Chong et al., Infect Immun 1996
:
By 4 h postexposure, viable organisms had
induced a 27-fold increase in IL-12
p40 mRNA levels while killed organisms had induced a 9-fold increase in
IL-12 p40 mRNA levels
Aloisi et al., J Immunol 1997
:
Combined stimulation with IFN-gamma/LPS enhances IL-12
p40 secretion and
induces IL-12 p75 secretion by microglia
Kishikawa et al., Toxicol Appl Pharmacol 1997
(Listeriosis) :
Support for the former hypothesis is based on the observation that Pb induced elevated levels of p40 splenic messenger RNA since increased
p40 expression would
result from lack of
IL-12 formation
Yoshimoto et al., J Immunol 1998
(Disease Susceptibility...) :
To investigate the antagonistic
effect of IL-12
p40 on
IL-12 activity in vivo, we generated transgenic ( Tg ) mice in which p40 gene was regulated by a liver-specific promoter