Yamada et al., Eur J Immunol 2004
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We show here that C1q suppresses IL-12p40 production in LPS stimulated murine bone marrow derived dendritic cells ( BMDC )
Csomor et al., Mol Immunol 2007
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Immobilized C1q induced maturation of MDCs and enhanced secretion of IL-12 and TNF-alpha, moreover, elevated their T-cell stimulating capacity
Baruah et al., Blood 2009
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Our novel data suggest that C1q augments the production of IL-12p70 by mouse and human DCs after CD40 triggering and plays important roles in sustaining the maturation of DCs and guiding the activation of T cells