Gene interactions and pathways from curated databases and text-mining

◀ Back to IGF2

BRCA1 — IGF2

Text-mined interactions from Literome

Shukla et al., Cancer Res 2006 (Mammary Neoplasms, Experimental) : Furthermore, we provide evidence that activation of IGF signaling by BRCA1 deficiency can also occur in a p53 independent fashion
Maor et al., Cancer Lett 2007 (Breast Neoplasms) : To assess the potential inhibitory role of BRCA1 on IGF-IR levels, we infected the BRCA1-deficient HCC1937 cell line with a BRCA1 encoding adenoviral vector ... Results of Western blots showed that BRCA1 induced a large reduction in endogenous IGF-IR levels
Schayek et al., Clin Cancer Res 2009 (Prostatic Neoplasms) : Tumor suppressor BRCA1 is expressed in prostate cancer and controls insulin-like growth factor I receptor ( IGF-IR ) gene transcription in an androgen receptor dependent manner ... On the other hand, BRCA1 enhanced IGF-IR levels in LNCaP C4-2 cells expressing an endogenous AR ... We provide evidence that BRCA1 differentially regulates IGF-IR expression in AR-positive and AR-negative prostate cancer cells
Li et al., Frontiers in bioscience (Landmark edition) 2013 (Prostatic Neoplasms) : BRCA1 can directly interact with the androgen receptor (AR) and Janus kinase ( JAK ), and can differentially regulate insulin-like growth factor 1 receptor ( IGF-IR ) expression in an AR-dependent manner