Gene interactions and pathways from curated databases and text-mining

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BOC — CASP7

Text-mined interactions from Literome

Yu et al., Oncogene 2005 (MAP Kinase Signaling System) : The caspase inhibitor Boc-D-fmk inhibited BAY 43-9006 induced caspase activation but not cytochrome c release
Oyarzo et al., Hum Pathol 2006 (Lymphoma, Large B-Cell, Diffuse) : We used the Karpas 299 and SU-DHL-1 cell lines, and the inhibitors Z-LEHD-FMK ( specific for caspase 9 ) and Boc-D-FMK ( general caspase inhibitor ) to investigate the role of caspase 9 activation in chemotherapy induced apoptotic cell death
Squires et al., J Biol Chem 2007 (Necrosis) : The caspase-1 inhibitor Boc-D-cmk blocked caspase-1 activity and membrane impairment in LT-treated cells
Klimaviciusa et al., Neurotoxicology 2008 : The BOC-D-FMK , the universal caspase inhibitor , completely reversed MK-801 induced DNA fragmentation, suggesting an apoptotic pathway of MK-801 induced cell death
Russell et al., J Neurobiol 1998 : Both IGF-I and Boc-aspartyl ( OMe ) -fluoromethylketone ( BAF ), a caspase inhibitor , equally reduced apoptosis after NGF withdrawal