◀ Back to IGF2

BMP7 — IGF2

Text-mined interactions from Literome

Bozić et al., Coll Antropol 2012 : We have investigated how BMP-7 regulates gene expression of BMP-4, Dentin matrix protein-1 (DMP-1), Insulin-like growth factor-I (IGF-I) and -II ( IGF-II ) in cementoblasts
Knutsen et al., Endocrinology 1995 : After 48 h of treatment, OP-1 increased the level of IGF-II ( 3- and 2-fold, respectively, at 100 ng/ml ) in the conditioned medium ( CM ) of SaOS-2 and TE85 human osteosarcoma cells with osteoblastic characteristics, whereas IGF-I levels were low to undetectable in the CM of either cell type
Yeh et al., Endocrinology 1996 : Osteogenic protein-1 mediated insulin-like growth factor gene expression in primary cultures of rat osteoblastic cells
Hayden et al., Endocrinology 1997 (Bone Neoplasms...) : Osteogenic protein-1 stimulates production of insulin-like growth factor binding protein-3 nuclear transcripts in human osteosarcoma cells
Yeh et al., J Cell Physiol 1998 : Osteogenic protein-1 regulates insulin-like growth factor-I (IGF-I), IGF-II , and IGF binding protein-5 (IGFBP-5) gene expression in fetal rat calvaria cells by different mechanisms ... On the other hand, the IGF-II nuclear pre-mRNA levels were increased by OP-1 but the half-life of the mature IGF-II mRNA was not affected ... In conclusion, OP-1 regulates IGF-I gene expression at the posttranscriptional level, but regulates IGF-II and IGFBP-5 gene expression at the transcriptional level