Gene interactions and pathways from curated databases and text-mining

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BCL2 — TPO

Text-mined interactions from Literome

Kirito et al., J Biol Chem 2002 : We further analyzed the signal transduction pathways required for TPO induced Bcl-xL gene expression
Nazareth et al., Lupus 2001 (Disease Models, Animal...) : We compared the effects of estrogen ( E2 ) and thrombopoietin (TPO) on the expression of Bax or Bcl-2 in bone marrow cells isolated from female non-lupus ( NZW or NZB parental strains ) or lupus-prone ( NZB and NZW cross ; NZB/W ) mice
Kozuma et al., Journal of thrombosis and haemostasis : JTH 2007 : Furthermore, pretreatment of UT-7/TPO with a phosphatidylinositol 3-kinase (PI3 K) inhibitor resulted in the cleavage of Bcl-xL even in the presence of TPO