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BCL10 — STAT3

Text-mined interactions from Literome

Rebbaa et al., Mol Med 2001 (Neuroblastoma) : Up-regulation of Stat3 phosphorylation and Bcl-xL expression, increased nuclear translocation of phospho-Stat3 , and binding to DNA occurred only in resistant SKN-SH/Dox6 cells
Schweizer et al., J Cell Biol 2002 (Facial Nerve Injuries) : Stat3 is essential for upregulation of Reg-2 and Bcl-xl expression in lesioned motoneurons
Zamo et al., Oncogene 2002 (Lymphoma, Large-Cell, Anaplastic) : NPM-ALK expression caused enhanced Bcl-x ( L ) transcription, largely mediated by Stat3
Yoshida et al., J Exp Med 2002 (Cell Transformation, Neoplastic...) : Activation of STAT3 by the HCV core in NIH-3T3 cells resulted in rapid proliferation and up-regulation of Bcl-XL and cyclin-D1
Konnikova et al., BMC cancer 2003 (Astrocytoma) : Moreover, STAT3 is required for the expression of the antiapoptotic genes survivin and Bcl-xL in the A172 glioblastoma cell line
Jing et al., DNA Cell Biol 2003 : We demonstrated that the G-rich ODN T40214, which forms a G-quartet structure at intracellular but not extracellular K+ ion concentrations, is delivered efficiently into the cytoplasm and nucleus of cancer cells where it inhibited IL-6 stimulated Stat3 activation and suppressed Stat3 mediated upregulation of bcl-x and mcl-1 gene expression
Bhonde et al., Oncogene 2005 (Carcinoma...) : UCN-01 inhibited the activating STAT3 phosphorylations on Ser727 and, notably, on Tyr705, but STAT3 did not contribute to Bcl-x ( L ) expression in colon carcinoma cells
Kim et al., Mol Endocrinol 2007 (Carcinoma, Papillary...) : Chromatin immunoprecipitation studies indicate that expression of LKB1 reduces the binding of STAT3 to its target promoters and suppresses STAT3 mediated expression of Cyclin D1, VEGF, and Bcl-xL
Lee et al., Int J Cancer 2008 (Carcinoma, Squamous Cell...) : A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas
Chen et al., J Mol Neurosci 2010 (Brain Neoplasms...) : In addition, down-regulation of Stat3 can suppress the expression of MMP-2, Bcl-xL and survivin but not 67LR
Ho et al., Cancer Sci 2010 (Lung Neoplasms...) : It was also demonstrated that IR enhances signal transducer and activator of transcription 3 ( STAT3 ) phosphorylation, and the reduction of STAT3 levels via RNA interference prevented IR-induced Bcl-X ( L ) accumulation, and thus all the tested Bcl-X ( L ) -dependent events
Glienke et al., Tumour Biol 2011 (Pancreatic Neoplasms) : siRNA targeting STAT3 was used to evaluate the role of STAT3 in modulating the expression of Survivin/BIRC5 and BCL-xL in the pancreatic cancer cell lines PANC-1 and BxPC-3 and induction of apoptosis
Zhao et al., Cytokine 2011 (Brain Injuries) : Moreover, AG490 attenuated rhEPO 's neuroprotection by down regulating rhEPO induced activation of JAK2/STAT3 , and inhibiting Bcl-2 and Bcl-xl
Zhang et al., Proc Natl Acad Sci U S A 2012 (Breast Neoplasms...) : BP-1-102 mediated inhibition of aberrantly active Stat3 in tumor cells suppresses the expression of c-Myc, Cyclin D1, Bcl-xL , Survivin, VEGF, and Krüppel-like factor 8, which is identified as a Stat3 target gene that promotes Stat3 mediated breast tumor cell migration and invasion
Tu et al., Cancer Lett 2012 (Bone Neoplasms...) : The inhibition of STAT3 in Saos-2 cells by siRNA or AG490 decreased cell proliferation, migration and invasion, down-regulated the mRNA expression of Cyclin D, Bcl-xL and Survivin and enhanced the apoptotic response
Zgheib et al., Eur Cytokine Netw 2012 (Cardiomegaly...) : Different effects of LIF were seen in protein levels of genes associated with STAT3 in the left ventricle : levels of SOD2 and Bcl-xL were unchanged, but levels of total STAT3 and MCP-1 were increased