Gene interactions and pathways from curated databases and text-mining

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BAD — IGF2

Text-mined interactions from Literome

Ahmad et al., J Immunol 2000 : In F/B cells, IGF-1 induced phosphorylation of the apoptotic protein BAD was inhibited by the PDE3 inhibitor cilostamide
Gilmore et al., J Biol Chem 2002 (MAP Kinase Signaling System) : Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor ... Moreover, we demonstrate that IGF transactivates the EGF receptor and that ZD1839 blocks IGF mediated phosphorylation of MAPK and BAD