Gene interactions and pathways from curated databases and text-mining

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BACE1 — CASP5

Text-mined interactions from Literome

Liu et al., Transplant Proc 2004 : The five groups included : group 1 ( n = 5 ), normal pancreata ; group 2 ( n = 7 ), pancreata stored in University of Wisconsin ( UW ) solution ( 4 degrees C ) for 6 hours ( hr ) ; group 3 ( n = 7 ), pancreata preserved in UW solution ( 4 degrees C ) for 18 hr ; group 4 ( n = 7 ), pancreata preserved in 0.9 % saline ( 4 degrees C ) for 6 hours ; and group 5 ( n = 5 ), pancreata preserved in 0.9 % saline ( 4 degrees C ) for 6 hours with Z-Asp-2,6-dichlorobenzoyloxymethylketone ( caspase inhibitor ) treatment
Sarajärvi et al., J Biol Chem 2009 : Increased caspase-3 activity coincided with a significant depletion of the BACE1 sorting protein, GGA3 ( Golgi localized gamma-ear containing ADP-ribosylation factor binding protein ), and subsequently augmented BACE1 protein levels and activity
Dong et al., Medical gas research 2011 : RNA interference mediated silencing of BACE and APP attenuates the isoflurane induced caspase activation