◀ Back to AKT1
AKT1 — AXL
Text-mined interactions from Literome
Lee et al., Oncogene 2002
(Ovarian Neoplasms) :
Akt is
required for
Axl-Gas6 signaling to protect cells from E1A mediated apoptosis ... Thus, we conclude that activated
Akt is
required for
Axl-Gas6 signaling to prevent E1A mediated apoptosis induced by serum deprivation
Cavet et al., Hypertension 2010
(Carotid Artery Diseases...) :
Blocking the Axl-MHC-IIB interaction with the specific myosin II inhibitor blebbistatin decreased phosphorylation of
Axl and
activation of extracellular signal regulated kinase 1/2 and
Akt
Ruan et al., EMBO J 2012
:
Axl is
essential for VEGF-A dependent activation of
PI3K/Akt
Linger et al., Oncogene 2013
(Carcinoma, Non-Small-Cell Lung...) :
Ligand dependent Mer or
Axl activation
stimulated MAPK,
AKT and FAK signaling pathways indicating roles for these RTKs in multiple oncogenic processes