Gene interactions and pathways from curated databases and text-mining

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AKT1 — AXL

Text-mined interactions from Literome

Lee et al., Oncogene 2002 (Ovarian Neoplasms) : Akt is required for Axl-Gas6 signaling to protect cells from E1A mediated apoptosis ... Thus, we conclude that activated Akt is required for Axl-Gas6 signaling to prevent E1A mediated apoptosis induced by serum deprivation
Cavet et al., Hypertension 2010 (Carotid Artery Diseases...) : Blocking the Axl-MHC-IIB interaction with the specific myosin II inhibitor blebbistatin decreased phosphorylation of Axl and activation of extracellular signal regulated kinase 1/2 and Akt
Ruan et al., EMBO J 2012 : Axl is essential for VEGF-A dependent activation of PI3K/Akt
Linger et al., Oncogene 2013 (Carcinoma, Non-Small-Cell Lung...) : Ligand dependent Mer or Axl activation stimulated MAPK, AKT and FAK signaling pathways indicating roles for these RTKs in multiple oncogenic processes