◀ Back to AKT1

AKT1 — AURKA

Pathways - manually collected, often from reviews:

• NCI Pathway Database Aurora A signaling: Aurora A (AURKA) → AKT1 (AKT1) (modification, activates) Yang et al., Int J Cancer 2006*
  Evidence: mutant phenotype, assay

Text-mined interactions from Literome

Long et al., Cell Signal 2013 (Leukemia, Myeloid, Acute) : AEG-1 overexpression is essential for maintenance of malignant state in human AML cells via up-regulation of Akt1 mediated by AURKA activation
He et al., American journal of translational research 2013 : Furthermore, we demonstrate that AURKA inhibition induced a remarkable downregulation of AKT activity and Bax induction