Gene interactions and pathways from curated databases and text-mining

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ATOH1 — NOTCH4

Text-mined interactions from Literome

Kazanjian et al., Gastroenterology 2010 (Colorectal Neoplasms) : ATOH1 is required for all effects of GSIs in intestinal crypts and adenomas ; Notch has no unique function in intestinal progenitors and cancer cells other than to regulate ATOH1 expression
Kelly et al., J Neurosci 2012 : Significantly, Atoh1 induces ectopic sensory patches through Notch signaling to form a cellular mosaic similar to the endogenous sensory epithelia and expansion of the sensory mosaic through the conversion of supporting cells and nonautonomous supporting cell production
Mizutari et al., Neuron 2013 (Hearing Loss, Noise-Induced) : Hair cell generation resulted from an increase in the level of bHLH transcription factor Atoh1 in response to inhibition of Notch signaling