Gene interactions and pathways from curated databases and text-mining

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ATG5 — CASP7

Text-mined interactions from Literome

Yousefi et al., Nat Cell Biol 2006 : Truncated Atg5 translocated from the cytosol to mitochondria, associated with the anti-apoptotic molecule Bcl-xL and triggered cytochrome c release and caspase activation
Polito et al., Br J Haematol 2009 (Lymphoma) : ATG-saporin-S6 induced a time dependent activation of caspase-3/7 in RAJI cells
Seillier et al., Cell Death Differ 2012 : Moreover, silencing the expression of autophagy related genes ( ATG5 or Beclin-1 ) or inhibiting caspase activity significantly decreases cell death induced by TP53INP1