Gene interactions and pathways from curated databases and text-mining

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AREG — CREB1

Text-mined interactions from Literome

O'Reilly et al., Am J Physiol Cell Physiol 2006 (Anoxia) : Hypoxia induces epithelial amphiregulin gene expression in a CREB dependent manner
Aguiari et al., J Mol Med (Berl) 2012 (Polycystic Kidney, Autosomal Dominant) : We now show by microarray analysis, luciferase assay, mutagenesis, and chromatin immunoprecipitation that CREB and AP1 contribute to increased expression of the amphiregulin gene, which codifies for an epidermal growth factor-like peptide, in ADPKD cystic cells, thereby promoting their cell growth