Gene interactions and pathways from curated databases and text-mining

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AQP9 — HIF1A

Text-mined interactions from Literome

Ding et al., Neurosci Lett 2009 (Brain Injuries) : Pharmacological inhibition of HIF-1alpha by 2ME2 reduced the up-regulated levels of AQP4 and AQP9 after TBI
Ali et al., Neurol Res 2012 (Brain Edema...) : Using a modified impact/head acceleration rodent model of diffuse TBI, we assessed the role of hypoxia inducible factor (HIF)-1alpha in regulating AQP9 expression and glycerol accumulation during the edema formation ... Compared to untreated but injured rats, inhibition of HIF-1alpha by 2ME2 significantly ( P < 0.05 ) reduced the TBI induced AQP9 up-regulation