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AQP9 — HIF1A
Text-mined interactions from Literome
Ding et al., Neurosci Lett 2009
(Brain Injuries) :
Pharmacological inhibition of
HIF-1alpha by 2ME2
reduced the up-regulated levels of AQP4 and
AQP9 after TBI
Ali et al., Neurol Res 2012
(Brain Edema...) :
Using a modified impact/head acceleration rodent model of diffuse TBI, we assessed the
role of hypoxia inducible factor
(HIF)-1alpha in regulating
AQP9 expression and glycerol accumulation during the edema formation ... Compared to untreated but injured rats, inhibition of
HIF-1alpha by 2ME2 significantly ( P < 0.05 )
reduced the TBI induced
AQP9 up-regulation