Gene interactions and pathways from curated databases and text-mining

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AP2S1 — CLTC

Pathways - manually collected, often from reviews:

  • KEGG Huntington's disease: Complex of 11 proteins → HTT (protein-protein, missing interaction)
  • Reactome Reaction: AP2S1 → CLTC (indirect_complex)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

  • STRING interaction: AP2S1 — CLTC (interaction, mapped from grid reactome)
  • STRING interaction: CLTC — AP2S1 (interaction, mapped from grid reactome)