Gene interactions and pathways from curated databases and text-mining

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ANG — CASP7

Text-mined interactions from Literome

Paudel et al., J Virol 2012 : Silencing ANG or inhibiting its nuclear translocation resulted in decreased nuclear LANA-1 and ANG levels, decreased interactions between ANG-LANA-1, ANG-p53, and LANA-1-p53, the induction of p53, p21, and Bax proteins, the increased cytoplasmic localization of p53, the downregulation of Bcl-2, the increased cleavage of caspase-3 , and the apoptosis of cells
Yang et al., Clin Exp Pharmacol Physiol 2012 : In addition, Ang- ( 1-7 ) inhibited AngII induced accumulation of cleaved caspase 3 and enhanced the expression of the anti-apoptotic factor Bcl-2 at both the mRNA and protein levels