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AMELX — NOS1
Text-mined interactions from Literome
Pisano et al., Dig Dis Sci 1999
:
AMG ( 100 mg/kg intragastrically )
induced an increase in
NO synthase type 2 (NOS2) activity, which was significantly different from control values, when AMG was administered 4 hr before the test
Armstrong et al., Scand J Gastroenterol 2000
(Colitis...) :
The aim of this study was to assess
aminoguanidine (AMG) , a selective
inhibitor of inducible
nitric oxide synthase , with regard to its effectiveness as a nitric oxide inhibitor and as a modulator of inflammation in trinitrobenzene sulfonic acid ( TNBS ) -induced colitis
Jenson et al., Eur J Immunol 2002
(Filariasis...) :
Treatment of Ag-stimulated cultures with
aminoguanidine (AMG) , an
inhibitor of inducible
nitric oxide synthase , rescued the CD4 ( + ) T cells from apoptosis and reversed the proliferative defect
Ding et al., Zhejiang Da Xue Xue Bao Yi Xue Ban 2003
(Sepsis) :
The hyporeactivity to vasoconstrictors was completely reversed by pretreatment either with
aminoguanidine (AMG) , a selective inducible
nitric oxide synthase inhibitor , or with 1H [ 1,2,4 ] oxadiazolo [ 4,3-a ] quininoxalin-1-one ( ODQ ), an inhibitor of NO-sensitive guanylyl cyclase
Li et al., World J Gastroenterol 2004
(Gastritis) :
AMG ( 75, 150 and 300 mg/kg ) could significantly
increase NO content and
NOS level in the stomach homogenates of mice compared with the model group ( P < 0.05, AMG 75 mg/kg and 150 mg/kg groups vs model group ; P < 0.01, AMG 300 mg/kg vs model group ) respectively
Papathanassiou et al., J Ocul Pharmacol Ther 2011
(Conjunctivitis) :
This study aimed at investigating the effects of ocular administration of
aminoguanidine (AMG) , a multiple action DAO and
NOS inhibitor , on the conjunctival histamine and nitrite levels in a model of experimental conjunctivitis