Gene interactions and pathways from curated databases and text-mining

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ALB — IGF1

Text-mined interactions from Literome

Ishida et al., Int J Mol Med 2004 : The production of albumin in osteoblastic cells was significantly enhanced in the presence of PTH, IGF-I , 17beta-estradiol or zinc sulfate
Lin et al., Zhongguo Zhong Yao Za Zhi 2005 (Bone Neoplasms...) : Deer serum albumin , with the molecular weight of 56.3 kDa, significantly increased the proliferation rate of the osteoblast-like UMR-106 cell and IGF-I secretion
Masumoto et al., Fukuoka Igaku Zasshi 1991 : Conversely, glucagon stimulated the production of IGF-I at concentrations over 10 ( -8 ) M, but inhibited the production of albumin at concentrations over 10 ( -10 ) M. Dexamethasone stimulated the production of IGF-I at concentrations over 10 ( -7 ) M, but had no significant effects on the production of albumin
Zvibel et al., J Cell Physiol 1995 (Carcinoma, Hepatocellular...) : In HepG2 cells, IGF II increased albumin mRNA levels and resulted in a shift from clusters of cells positive to 100 % of the cells expressing immunohistochemically detectable albumin ... In FTO-2B cells, IGF II increased the expression of albumin , CK19, and GGT, without accompanying changes in albumin and GGT mRNAs
Ballmer et al., J Clin Invest 1995 (Acidosis...) : The effect on albumin synthesis may be mediated , at least in part, by a suppression of insulin-like growth factor-I , free thyroxine and tri-iodothyronine
Gronowski et al., Endocrinology 1996 : The activation of insulin-like growth factor I and Spi 2.1 gene expression and the inhibition of albumin transcription also are not blocked by CHX, suggesting that these effects are primary consequences of GH-activated signal transduction pathways