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ALB — CASP5

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Murayama et al., J Cell Sci 2004 (Neoplasms) : For the possible mechanism of ALB6 induced apoptosis, ALB6 activated the c-Jun NH2-terminal kinase/stress activated protein kinase ( JNK/SAPK ) and p38 mitogen-activated-protein kinase ( MAPK ) within 5-15 minutes, as well as caspase-3 within 24-48 hours ... It is noteworthy that ALB6 induced tyrosine phosphorylation of the p46 Shc isoform specifically and that the overexpression of its dominant negative form completely suppressed the ALB6 induced activation of JNK/SAPK, p38 MAPK and caspase-3 , resulting in the inhibition of apoptotic cell death
Higuchi et al., Curr Eye Res 2007 (Disease Models, Animal...) : Apoptosis suppression assay using cell lines revealed that caspase-3 activation induced by serum deprivation and DNA fragmentation induced by addition of apoptosis inducers were dose-dependently suppressed by albumin
Brezniceanu et al., J Am Soc Nephrol 2010 (Diabetic Nephropathies...) : In vitro, albumin stimulated activity of both caspase-12 and caspase-3 as well as expression of caspase-12 and CCAT/enhancer binding protein homologous protein in a human proximal tubule cell line ( HK-2 )