Gene interactions and pathways from curated databases and text-mining

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AKT1 — NPY

Text-mined interactions from Literome

Frago et al., J Neuroendocrinol 2005 : Furthermore, inhibition of Akt activation by LY294002 treatment did not inhibit GHRP-6 induction of NPY or IGF-I synthesis
Anitha et al., Gastroenterology 2006 : NPY increased the phosphorylation of Akt , a downstream target of the PI-3-kinase pathway
Son et al., J Cell Mol Med 2011 : Our results indicate that both Y1 and Y5 receptors appear to be involved in the NPY mediated activation of AKT/protein kinase B and extracellular signal regulated kinase 1/2 ( ERK1/2 ) in hESCs
Hong et al., PLoS Genet 2012 : Conversely, AKT mediated insulin signaling suppressed FOXO mediated sNPF/NPY expression, which resulted in decreasing food intake