Gene interactions and pathways from curated databases and text-mining

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ADM — CASP7

Text-mined interactions from Literome

Sasaki et al., Jpn J Cancer Res 2001 (Adenocarcinoma...) : NAC additionally inhibited caspase-3 activity induced by ADM treatment, while Ac-DMQD-CHO showed no suppressive effect on reactive oxygen species ( ROS ) ... Stable antisense-TNF transfectants showed higher ADM sensitivity and greater ADM induced ROS production and caspase-3 activity than mock transfectant or parent cells
Domínguez-Rodríguez et al., Anticancer Res 2004 : In these experimental conditions, ADM induced AP in a mainly caspase-9 dependent manner and this was related to a reduction in the deltapsim