Gene interactions and pathways from curated databases and text-mining

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ADCY9 — EPO

Text-mined interactions from Literome

Miller et al., Blood 1991 : Epo did not inhibit but significantly stimulated adenylate cyclase activity
Setchenska et al., Acta Physiol Pharmacol Bulg 1990 : Erythropoietin ( 0.2 U/ml ) causes a transient increase in the activity of adenylate cyclase , which is maximal by 20 min incubation of the cells in the presence of the hormone and disappears within 4 hours
Setchenska et al., Mol Cell Endocrinol 1988 : Independent activation of adenylate cyclase by erythropoietin and isoprenaline ... The stimulation of adenylate cyclase by erythropoietin was observed also in the presence of the beta-antagonist propranolol, when both were added either to whole cells or to isolated membranes
Setchenska et al., Biomed Biochim Acta 1987 : The effect of erythropoietin on the adenylate cyclase activity of rabbit bone marrow erythroblasts ... Erythropoietin could also stimulate the basal activity of adenylate cyclase in an in vitro assay containing plasma membranes of immature, but not mature, erythroid cells ... It is suggested that erythropoietin activates the adenylate cyclase of immature erythroblasts via a receptor and a guanine nucleotide binding protein with high affinity for GTP
Bonanou-Tzedaki et al., Eur J Biochem 1986 : Stimulation of the adenylate cyclase activity of rabbit bone marrow immature erythroblasts by erythropoietin and haemin ... Erythropoietin but not haemin can stimulate the basal activity of adenylate cyclase in an in vitro assay containing plasma membranes of immature erythroid cells ... In the presence of guanine nucleotides the activation of adenylate cyclase by erythropoietin is increased further but the effect is not additive