Gene interactions and pathways from curated databases and text-mining

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ADCY10 — MAPK6

Text-mined interactions from Literome

Ameri et al., Prog Neurobiol 1999 : The CB1 receptor mediates inhibition of adenylate cyclase , inhibition of N- and P/Q-type calcium channels, stimulation of potassium channels, and activation of mitogen activated protein kinase ... The CB2 receptor mediates inhibition of adenylate cyclase and activation of mitogen activated protein kinase
Suh et al., J Cell Biochem 2008 : On the other hand, inhibition of each pathway by SQ 22536 ( adenylate cyclase inhibitor ), LY 294002 ( PI3-K phosphatidylinositol 3-kinase inhibitor ), Akt inhibitor, staurosporine ( PKC inhibitor ), PD 98059 ( MEK inhibitor ), SB 203580 ( p38 MAPK inhibitor ), or SP 600125 ( JNK inhibitor ) blocked 30 mM glucose induced AQP8 translocation, respectively
Zondag et al., Biochem J 1998 : Sphingosine 1-phosphate ( S1P ) and lysophosphatidic acid (LPA) are structurally related lipid mediators that act on distinct G-protein coupled receptors to evoke similar responses, including Ca2+ mobilization, adenylate cyclase inhibition , and mitogen activated protein ( MAP ) kinase activation
Okamoto et al., J Biol Chem 1998 : EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen activated protein kinase activation, and adenylate cyclase inhibition