Gene interactions and pathways from curated databases and text-mining

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ADCY1 — AKT1

Text-mined interactions from Literome

Suh et al., J Cell Biochem 2008 : On the other hand, inhibition of each pathway by SQ 22536 ( adenylate cyclase inhibitor ), LY 294002 ( PI3-K phosphatidylinositol 3-kinase inhibitor ), Akt inhibitor, staurosporine ( PKC inhibitor ), PD 98059 ( MEK inhibitor ), SB 203580 ( p38 MAPK inhibitor ), or SP 600125 ( JNK inhibitor ) blocked 30 mM glucose induced AQP8 translocation, respectively
Hayashi et al., Thromb Haemost 2009 : The phosphodiesterase-3 ( PDE3 ) inhibitors cilostamide and cilostazol, and the adenylate cyclase activator forskolin, inhibited collagen induced Akt phosphorylation at Ser473