◀ Back to AKT1

ACLY — AKT1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: ACLY → AKT1 (directlyIncreases, ACLY Activity) Berwick et al., J Biol Chem 2002*
  Evidence: Furthermore, ATP-citrate lyase was phosphorylated in vitro by recombinant protein kinase B on the same site. Taken together, these results demonstrate that serine 454 of ATP-citrate lyase is a novel and major in vivo substrate for protein kinase B.

Text-mined interactions from Literome

Sale et al., Biochemistry 2006 : Role of protein kinase B in phosphorylating glycogen synthase kinase-3, tuberin, WNK1, and ATP citrate lyase
Migita et al., Cancer Res 2008 (Adenocarcinoma...) : The introduction of constitutively active Akt into cells enhanced the phosphorylation of ACLY , whereas dominant negative Akt caused attenuation