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ABCB1 — AKT1

Text-mined interactions from Literome

Wang et al., Cancer Lett 2010 (Ovarian Neoplasms) : Meanwhile, the further study demonstrates that the chemoresistance caused by IL-6 is associated with increased expression of both multidrug resistance related genes ( MDR1 and GSTpi ) and apoptosis inhibitory proteins ( Bcl-2, Bcl-xL and XIAP ), as well as activation of Ras/MEK/ERK and PI3K/Akt signaling
Mukherjee et al., Proc Natl Acad Sci U S A 2013 : The innate immune receptor, Toll-like receptor 2/6 heterodimer, is exploited by Sb ( R ) LD to activate ERK and nuclear translocation of NF-?B involving p50/c-Rel leading to IL-10 induction, whereas MDR1 up-regulation is mediated by PI3K/Akt and the JNK pathway