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ABCA1 — PRKAR2A

Text-mined interactions from Literome

See et al., J Biol Chem 2002 : Furthermore, we demonstrate that phosphorylation of ABCA1 is mediated by protein kinase A (PKA) or a PKA-like kinase in vivo ... These studies demonstrate a novel serine ( Ser-2054 ) on the ABCA1 protein crucial for PKA phosphorylation and for regulation of ABCA1 transporter activity
Haidar et al., J Lipid Res 2002 (Tangier Disease) : In contrast, H-89 PKA inhibitor reduced cellular cholesterol efflux by 70 % in a dose dependent manner and inhibited almost completely ABCA1 phosphorylation
Tang et al., J Biol Chem 2004 (Fibrosarcoma) : Conversely, PKA but not JAK2 inhibition significantly reduced the intrinsic cholesterol translocase activity of ABCA1
Rubic et al., Biochem Pharmacol 2004 : The niacin effect on CD36 but not on ABCA1 was prevented by cyclooxygenase inhibition, whereas the niacin effect on ABCA1 but not on CD36 was prevented by PKA inhibition, suggesting mediation by the 15d-PGJ2/PPARgamma and the cAMP/PKA pathways, respectively
Liu et al., J Cardiovasc Pharmacol 2010 : PKA-specific activation by PKA agonist enhanced the upregulation of ABCA1 serine phosphorylation and ABCA1 mediated cholesterol efflux by D4-F
Nakaya et al., Atherosclerosis 2010 : Cilostazol did not change intracellular cAMP levels in THP-1 macrophages and RAW264.7 cells, and a protein kinase A (PKA) inhibitor did not affect cilostazol induced ABCA1 and ABCG1 expression
Ma et al., J Biol Chem 2012 (Atherosclerosis) : We present evidence that ABCA1 activates PKA and that this elevated PKA activity contributes to M2-like inflammatory response from ABCA1 ( +/+ ) bone marrow derived macrophages