Gene interactions and pathways from curated databases and text-mining

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AANAT — MAPK6

Text-mined interactions from Literome

Man et al., Endocrinology 2004 : In this study we investigated whether p38 ( MAPK ) played a role in the adrenergic regulation of arylalkylamine-N-acetyltransferase ( AA-NAT ) induction and melatonin ( MT ) synthesis ... Cotreatment with SB202190, a selective p38 ( MAPK ) inhibitor, although having no effect on AA-NAT activity or protein level 3 h after NE treatment, caused a sustained increase in AA-NAT activity and protein level after 6 h of NE treatment
Ho et al., Mol Cell Endocrinol 2006 : Studies with selective MAPK inhibitors reveal a modulating effect of MAPKs on arylalkylamine-N-acetyltransferse ( AA-NAT ) activity, with involvement of p42/44MAPK in the induction of AA-NAT and p38MAPK participating in the amplitude and duration of the AA-NAT response ... These effects of p42/44MAPK and p38MAPK on AA-NAT activity match their timing of activation